Rheumatoid Arthritis Factor

AsseyMethod: Nephelometric
Abbrevation: RF (quantitative qualitative )
Sector: Immunology
SampleType: S
S.Vol: -
Transport: at 4˚c, -20˚c
Storage: 4 day at 4˚c,for longer time at -20˚c
Test Name: Rheumatoid Arthritis Factor
Normal Range: Negative

This test is related to
Why get tested?

To help diagnose rheumatoid arthritis (RA) and Sjögren’s syndrome

When to get tested?

When your doctor thinks that you have symptoms suggestive of RA or Sjögren’s syndrome

Sample required?

A blood sample taken from a vein in your arm

Test preparation needed?

None required


What is being tested?

This test detects and measures rheumatoid factor (RF), a type of “autoantibody”, in the blood. We all have antibodies (also known as immunoglobulins) in our blood, which are protective proteins which defend the body against infection, particularly from bacteria. However, “autoantibodies” may attack the patient’s own tissues mistakenly identifying them as “foreign”. While the role of RF is not well understood, it may not directly cause joint damage, but promote the body's inflammation reaction which in turn contributes to autoimmune joint destruction.  

The RF test is sensitive but not very specific, it can be found in diseases other than rheumatoid arthritis (RA).  It is most closely associated with RA but may also be present in other autoimmune disorders, such as Sjögren’s syndrome, in some persistent bacterial and viral infections, and can be found in a small but significant percentage of healthy people particularly in the elderly.

How is the sample collected for testing?

A blood sample is collected from a vein in your arm.

Is any test preparation needed to ensure the quality of the sample?

None required