Sector: Hormone 1
Transport: at 2-8˚c, -20˚c
Storage: 1 day at 2-8˚c for longer time at -20 ˚c
Test Name: Thyrogolobulin
Normal Range: Up to 70
To monitor treatment of some types of thyroid cancer and to look for return of the cancer
Once treatment for thyroid cancer has been completed, before and after radioactive iodine therapy for thyroid cancer, and at varying intervals to monitor for recurrence.
A blood sample taken from a vein in your arm
No fasting or special preparation is required before the test. In order to increase the ability of the test to pick up very small amounts of remaining thyroid cells some patients may be asked to stop taking their thyroid hormone replacement tablets prior to the test or be given injections (recombinant TSH) in an attempt to stimulate thyroglobulin production. Dietary supplement rich in vitamin B7 (Biotin) should not be taken in the day before the test in order to avoid test interference that many lead to false results. Please follow any instructions you are given by your Doctor, prior to having this blood test.
The thyroid gland is a small butterfly shaped organ that helps to regulate the rate at which the body uses energy. The thyroid lies flat against the windpipe in the throat and is composed primarily of very small, ball-shaped structures called follicles. This test measures the amount of thyroglobulin in the blood.
Thyroglobulin is a protein produced by follicle cells and stored in the thyroid gland. Thyroglobulin is broken down to release the thyroid hormones T4 (thyroxine) and T3 (triidothyronine) when needed. The production of these hormones and their release into the blood stream is stimulated by the hormone TSH (thyroid stimulating hormone). No other part of the body makes thyroglobulin, but it is produced by many thyroid cancers – both those confined to the thyroid gland and those that have spread to other parts of the body. Thyroglobulin is a tumour marker but concentrations in the blood can be increased in other thyroid disorders.