Abbrevation: Ccp Ab
Sector: Hormone 2
Transport: at 4˚c, -20˚c
Storage: 4 weeks at 4˚c,for longer time at -20˚c
Test Name: Cyclic Citrullinated Peptide
Normal Range: -
To help in the diagnosis of rheumatoid arthritis (RA) and differentiate it from other types of arthritis; sometimes to help evaluate the prognosis of a patient with RA
If a patient has joint inflammation and/or undiagnosed or undifferentiated inflammatory polyarthritis (symptoms which may suggest but do not yet meet the criteria of RA) and the doctor suspects RA
A blood sample taken from a vein in your arm
The cyclic citrullinated peptide antibody (CCP) test detects the presence of anti-citrulline antibodies in the blood. Citrulline is an unusual amino acid (protein building block), which is created when the amino acid arginine is altered. There is speculation that conversion of arginine to citrulline resulting in “citrullinated” proteins in the lining of joints, may be the target of anti-CCP antibodies in RA, which may contribute to inflammatory process in RA.
How is the sample collected for testing?
A blood sample is obtained by inserting a needle into a vein in the arm.
Is any test preparation needed to ensure the quality of the sample?